Schaffner, Florence
자료유형 | 단행본 |
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개인저자 | Schaffner, Florence.,editor. Merlin, Jean-Louis.,editor. von Bubnoff, Nikolas.,editor. |
단체저자명 | SpringerLink (Online service). |
서명/저자사항 | Tumor Liquid Biopsies [electronic resource] / edited by Florence Schaffner, Jean-Louis Merlin, Nikolas von Bubnoff. |
판사항 | 1st ed. 2020. |
형태사항 | VI, 368 p:online resource. |
총서사항 | Recent Results in Cancer Research=2197-6767 ;215 |
총서부출표목 | Recent Results in Cancer Research,215 |
기본자료 저록 | Springer Nature eBook |
기타형태 저록 | Printed edition:9783030264383Printed edition:9783030264406Printed edition:9783030264413 |
ISBN | 9783030264390 |
기타표준부호 | 10.1007/978-3-030-26439-0 |
내용주기 | Circulating Tumor Cells: Pathophysiology of Tumor Cell Release into the Circulation and characterization of CTC -- CTC enrichment technologies -- Genotyping of CTC :example Lung cancer -- CTC in Breast Cancer: a clinical approach -- Circulating Tumor DNA: Pathophysiology of ctDNA Release into the Circulation and its characterization -- Enrichment and Analysis of ctDNA -- ctDNA in Lung Cancer -- ctDNA in Breast Cancer -- ctDNA in Colorectal Cancer -- Dynamic Treatment Stratification using ctDNA -- Circulating Tumor RNA: Noncoding Tumor RNAs: Pathophysiology of Release and Techniques of Detection -- Circulating miRNAs as Biomarker in Cancer -- Plasma Subcompartments as Source for Tumor derived Biomarkers: Exosomes and Vesicles as Biomarker in Cancer -- Quantitative proteomic Analysis of Plasma in Cancer. |
요약 | This book is a comprehensive guide to the techniques, clinical applications, and benefits of the different forms of liquid biopsy employed in patients with a variety of tumor types, including lung, breast and colorectal cancer. Offering detailed explanations, it discusses the how changes in tumors can be tracked using these cutting-edge technologies, which enable the detection and analysis of diverse circulating biomarkers: tumor cells, tumor DNA, tumor RNA (free or in exosomes), and fluid biomarkers identifiable by means of targeted proteomics. The use of such advanced technologies is enabling us to tackle questions and problems in a way that was not possible just a few years ago. We now have at our disposal an effective means of overcoming the problem of intratumor heterogeneity, which has limited the value of conventional biopsy approaches. As a consequence, oncology practice is about to change radically, toward truly personalized precision medicine. This book provides both clinicians and researchers with a thorough and up-to-date overview of progress in the field. |
일반주제명 | Oncology. Pathology. Cancer. Oncology. Pathology. Cancer Biology. |
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