상세정보
- 상세정보
Antibodies for Treating Cancer Basics, Development, and Applications [electronic resource]
Little, Melvyn
- 책이미지
-
- 도서 상세정보
- 서평쓰기
| 자료유형 | 단행본 |
|---|---|
| 개인저자 | Little, Melvyn.,author. |
| 단체저자명 | SpringerLink (Online service). |
| 서명/저자사항 | Antibodies for Treating Cancer [electronic resource] : Basics, Development, and Applications / by Melvyn Little. |
| 판사항 | 1st ed. 2021. |
| 형태사항 | XI, 151 p. 34 illus. in color:online resource. |
| 기본자료 저록 | Springer Nature eBook |
| 기타형태 저록 | Printed edition:9783030725983Printed edition:9783030726003Printed edition:9783030726010 |
| ISBN | 9783030725990 |
| 기타표준부호 | 10.1007/978-3-030-72599-0 |
| 내용주기 | 1 Life-saving antibodies – history of immunization -- 2 Current approaches for immunising against cancer -- 3 Function and Structure of antibodies -- 4 Of mice and men - production of therapeutic antibodies -- 5 Novel modular antibodies -- 6 Antibodies as “Magic Bullets” -- 7 Mediation of tumor cell destruction -- 8 Engagement of immune killer cells -- 9 Approved antibodies for cancer therapy -- 10 Bringing therapeutic antibodies on the market -- 11 Future developments – outlook. |
| 요약 | This book presents a compact overview of the history, evolution and fascinating novel applications of antibodies for the treatment of cancer, leading the reader step by step to the latest advances. Interesting anecdotes, together with self-explanatory and clearly structured figures with a humorous touch, facilitate the reader’s understanding of this complex topic. Clinical cases round out the book, making it a valuable aid for professionals in their everyday practice. The growing importance of the topics covered here was highlighted by the joint award of the 2018 Nobel Prize in Chemistry to Frances H. Arnold (directed evolution of enzymes), George P. Smith (phage display of peptides) and Sir Gregory P. Winter (phage display of antibodies). Furthermore, the 2018 Nobel Prize in Physiology or Medicine was awarded to James P. Allison and Tasuku Honjo for their discovery of cancer therapy by inhibition of negative immune regulation. Many of the antibodies that are now being brought to market target precisely these immune checkpoint modulators. The book addresses a broad readership, ranging from professionals and experts in the field to residents and medical students. |
| 일반주제명 | Oncology. Cancer—Treatment. Oncology. Cancer Therapy. |
| 바로가기 | URL |